As was mentioned, the "wildcat" rounds being shot now have long distance capability.
250-300 yards I am sure would be no issue for them in the right hands and given target exposure.

My primary deer hunting weapon is an Ultra light arms smokeless muzzleloader. With the bullet and powder load I use, a steady rest and clear view of the vitals, I could kill a deer well past 250 yards, approaching 300 yards. Since Smokeless muzzleloaders have been legal in Indiana for many years now, several years prior to the 'wildcat' centerfire rifle rounds, I have heard of zero incident regarding stray bullets or related injury.

If Indiana lawmakers pass it, I am fine with the idea! No problem here.